Fig. 9: Aberrant production of inflammatory cytokines caused by Gadd45g deficiency. | Nature Communications

Fig. 9: Aberrant production of inflammatory cytokines caused by Gadd45g deficiency.

From: Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms

Fig. 9

a Serum concentrations of IL-1β, IL-2, IL-4, IL-6, IL-10, IL-12 p70, IL-17A, CCL2, CCL3, G-CSF, GM-CSF, PDGF-AA, IFN-γ and S100a9 in the Gadd45g+/− mice with MPN and their age-matched controls (n =  3 mice per group). b Comparisons of serum concentrations of IL-4 and IL-6 between GADD45ghigh (n = 5) and GADD45glow (n = 4) patients with MPN. Data are shown as means ± SD, two-tailed Student’s t test.

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