Fig. 3: UHRF1-depleted cells show more severe DNA hypomethylation than DNMT1-depleted cells.
From: Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
A Global DNA methylation analysis in the indicated HCT116 derivatives after auxin treatment for the indicated duration (LUMA). Error bars represent the SEM of biological triplicates. B As in (A), but the quantitation of 5-mC was done by LC-MS/MS. C As in (A), but the quantitation of DNA methylation was done by WGBS. D LUMA analysis on cells treated with auxin or 5-aza. U: UHRF1-AID; D: DNMT1-AID; UD: UHRF1-AID/DNMT1-AID. E Western blotting on 5-Aza-treated cells. Experiments in each panel were performed two times, and the representative results are shown. Source data are provided as a Source data file.
