Fig. 1: State of the art for the stereodivergent synthesis of axially chiral alkene analogs.

A Z/E isomerization of di- and tri-substituted alkenes. B Z/E isomerization of tetrasubstituted alkenes. C Asymmetric allylic substitution-isomerization and photocatalytic geometrical Z/E isomerization. D Stereodivergent synthesis of axially chiral N-vinylquinolinones.