Fig. 4: Egocentric social vector representations are context dependent.
From: Multiplexed representation of others in the hippocampal CA1 subfield of female mice
a Diagram of the experimental paradigm. An imaged mouse (blue) interacted freely with a partner in three different contexts. Scale bar: 10 cm. Representative examples (as in Fig. 1e) of cells classified as egoSVC (asterisk) in at least one of two consecutive sessions, testing for effects of size (b) or shape (c). Scale bar: 20 cm. d, e Venn diagrams representing overlaps between subpopulations of cells classified as egoSVC in consecutive sessions (4 imaged mice, 1003 imaged cells; overlap indexes sessions 1 vs. 2: 1.20, Binomial test p = 0.58; sessions 2 vs. 3: 1.73, Binomial test p = 0.30). f, g Cumulative distribution of the normalized dot product, quantifying the similarity of the mean firing rate of egoSVCs across halves in the same context (violet) or across contexts (gray) of different size (f) or shape (g). Halves of sessions in the same context were more similar than in different contexts (27 sets of paired sessions, two-tailed Mann–Whitney test, sessions 1 vs. 2: Mann–Whitney U = 0, Cliff’s Delta = 1, p = 10−15; sessions 2 vs. 3: Mann–Whitney U = 0, Cliff’s Delta = 1, p = 4 × 10−15). Source data are provided as a Source Data file.
