Table 1 Summary of demographic and clinical characteristics from the study cohorts

Age

Median (SD)

68.0 (10.6)

67.0 (9.5)

66.5 (9.25)

0.0341ⁱ

Gender, n (%)

0.5753^ƚ

Male

122 (61%)

63 (47%)

39 (63%)

Female

77 (39%)

70 (53%)

23 (37%)

P Stage (AJCC 7th ed.), n (%)

0.4751^ƚ

0

4 (1.96%)

1 (0.73%)

-

I

114 (55.88%)

50 (36.76%)

-

II

41 (20.09%)

47 (35.33%)

2 (3%)

III

40 (19.60%)

34 (25%)

60 (97%)

Histology, n (%)

0.0375

Adenocarcinoma

154 (80%)

89 (67%)

-

Squamous cell

39 (20%)

31 (23%)

-

Other

6 (3%)

13 (10%)

-

Smoking History, n (%)

0.1056

Smoking

157 (79%)

111 (83%)

-

Never

42 (21%)

22 (17%)

-

RNA Sequence, n (%)

Available

115 (58%)

93 (70%)

-

ctDNA, n (%)

-

At baseline prior to surgery

-

72 (54%)

-

Clearance status after surgery

-

50 938%)

-

Median Follow-up time (months)

50

44

20

0.07^ƚ

Median OS time (months)

35

20

13

0.24^ƚ

Recurrence Free Survival, n (%)

0.5658

Recurrence (1)

73 (37%)

42 (32%)

-

No Recurrence (0)

126 (63%)

91 (68%)

-

Overall Survival, n (%)

0.03751^ƚ

Dead (1)

92 (46%)

30 (23%)

41 (72%)

Alive (0)

107 (54%)

103 (77%)

16 (28%)