Fig. 3: Skin grafts generated in p63 knockout chimera could be engrafted for a long time despite the allogeneic dermis.
From: Skin graft with dermis and appendages generated in vivo by cell competition
a Experimental schematic of semi-autologous skin grafting. Created with BioRender.com. b Macroscopic image after semi-autologous transplantation. POD postoperative day. c Immunofluorescence staining of the boundary of grafts and recipients in semi-autologous transplantation (upper panel) and autologous transplantation (lower panel) at 91 POD. White arrows indicate the boundary between skin grafts (EGFP−) and recipient skin (EGFP+). EGFP, host cells; DAPI, nuclear; p63, basal cell marker; KRT14, mature keratinocyte. Scale bars, 20 μm. d Experimental groups and graft survival curves of orthotopic skin transplantations. Source data are provided with this paper.
