Fig. 4: Burst amplitude is reduced during drawing in comparison to the rest interval and reduced by deep brain stimulation.
From: Subthalamic stimulation modulates context-dependent effects of beta bursts during fine motor control
Single trials, distributions, mean and standard deviation of the mean burst amplitude are plotted for the different conditions and intervals (blue = free drawing without stimulation, draw: −0.108 arbitrary units (arb. units) ±0.269 (mean ± standard deviation), n = 149, rest: −0.024 arb. units ±0.321, n = 164; red = free drawing with stimulation, draw: −0.102 arb. units ±0.202, n = 153, rest: −0.084 arb. units ±0.208, n = 156; green = template-guided drawing without stimulation, draw: −0.110 arb. units ±0.263, n = 157, rest: −0.042 arb. units ±0.316, n = 172; orange = template-guided drawing with stimulation, draw: −0.128 arb. units ±0.195, n = 167, rest: −0.097 arb. units ±0.221, n = 173). Two-sided linear mixed-effects model revealed significant effects of movement interval (P < 0.001), stimulation (P < 0.001), as well as a significant interaction between stimulation and movement interval (P = 0.018). The top lines indicate the results from the significant post hoc tests (two-sided, bonferroni corrected), combined across the drawing conditions (free and template): a rest_off > draw_off, P < 0.001; b rest_off > rest_on, P < 0.001; c rest_off > draw_on, P < 0.001; d draw_off > draw_on, P < 0.0012. *P < 0.05 (Bonferroni corrected). Source data are provided as a Source Data file.
