Fig. 4: Survival analysis in the ISARIC4C cohort (n = 112 patients).

A Forest plot of the Hazard Ratio (HR) from Cox regression analysis shows a higher risk of death for older patients and a lower risk for patients with higher LEF1-AS1 expression level. The dots and the error bars display the HR and the confidence interval, respectively. The p values are from a two-sided Wald test. B Kaplan–Meier curves using the stratified LEF1-AS1 expression with the first quartile (Q1), the median and the third quartile (Q3), respectively. Patients with LEF1-AS1 expression levels below or equal to the first quartile (Q1) are at a high risk of death. The p values are from a two-sided log-rank test.