Fig. 2: Evaluation of CLASP performance.

A Comparison of CLASP annotations to published protein localization information (blue pie chart, left) and breakdown of CLASP annotations that disagree with previous reports or relate to previously unannotated proteins (orange pie chart, right). Annotations of individual proteins are shown in Supplementary Data 5. B, C Number (B) and percentage distribution (C) of mitochondrial protein localization annotations by CLASP and in published proximity biotinylation resources7,29. The columns are sub-divided to indicate the spatial specificity of the localization annotations. D Estimated information yield of a single CLASP experiment and single BioID experiments in7 and29, calculated as the total number of single sub-compartment annotations divided by the total number of assays. Source data are provided as a Source Data file.