Fig. 2: Normalized expression of Tier 1 targets across pediatric cancer types and normal tissues.
From: Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression
The heatmap uses a blue-red color scale to display the mean expression rank (range 0–1) of exon FPKM value of RNA-seq samples profiled for a normal tissue (n = 7460) or a specific tumor type (n = 1532). 37 Tier 1 targets are grouped by their biological functions on the left, while the gene names, status on AS exon, oncofetal protein, cellular localization, and expression prevalence in normal bone marrow are shown on the right. One representative exon is shown for a gene-level target. Expr expression, BM bone marrow, NA not available.
