Fig. 1: Diverse patterns of interhemispheric connections.

A Two dorsal-view cortical flat maps from the CCFv3, showing 43 cortical regions and injection sites in various mouse strains from the Allen Mouse Connectivity Atlas (Allen population)^16,18. Refer to Supplementary Data 1, and 2 for strain and experimental details, and Supplementary Data 3 for full brain region names. The third panel depicts the injection sites of ION single-neuron data^17,38. B Illustrations of the connection types, including intrahemispheric-heterotopic, interhemispheric-heterotopic, and homotopic connections. C Connectivity matrices of wild-type mice from Allen population data, with layer-specific Cre mice data presented in Supplementary Fig. 1C and E, F. Aud.: auditory cortex. D Weighted (upper two rows) and binary (lower two rows) connectivity matrices of the PFC projectome based on ION single-neuron data and Allen population data, respectively. E Projection types (left) and their derived seven neuron/region types. The corresponding neuron IDs of neuron-type illustration are provided in Supplementary Data 4. F Composition of regional types in the Allen population data (top) and neuronal types in the ION single-neuron data (bottom). G Laminar distribution of neuronal types from ION single-neuron data. H Regional compositions of different neuronal types from ION single-neuron data. Source data of (C, D) are provided as a Source Data file.