Fig. 3: Network dynamics modeling of homotopic region pairs.
A Diagram of the network model, including four bilateral areas (Xi, Xc, Yi, and Yc) and three types of projections: self-projections (green), homotopic projections (blue), and heterotopic projections (orange). B Illustration of the three structural features: heterogeneity, homotopic strength, and self-homotopic overlap. Homotopic correlation demonstrates a decline with higher heterogeneity (C), and an increase with stronger homotopic connections and greater self-homotopic overlap (D, E), across varying noise conditions (0.05, 0.1, 0.2). Discrepancies in the FC variation range attributable to heterogeneity against those due to homotopic strength (F) and self-homotopic overlap (G), respectively. For visualization clarity, a second-order polynomial model fits the trend lines. The difference in variation range (Δvariation range) consistently increases with larger N under different noise levels (0.05, 0.1, 0.2). Source data of (C–G) are provided as a Source Data file.
