Fig. 6: Proteome functional redundancy.
From: Freshwater genome-reduced bacteria exhibit pervasive episodes of adaptive stasis
a, c Structural alignments of the substrate binding protein (K02051) belonging to the NitT/TaUt family transport system. Each colour corresponds to one protein. These panels illustrate the levels of functional redundancy observed in the SPs of large (a) and small (c) genome species. The degree of structural similarity is quantified using the Q-score, while the number of overlaps indicates the aligned proteins (seven in (a), and two in (c)). Burkholderiaceae sp. 4 and Ilumatobacteraceae sp. 4 were selected as representatives of the large and small genomes species, respectively, due to their maximum number of NitT/TaUt substrate-binding proteins per species. b Analysis of functional redundancy ratios in CPs and SPs (Large CP n = 192; SP n = 192; Small CP n = 150; SP n = 150). Wilcoxon rank-sum tests were conducted to compare values within the SP category (P value < 2.2e-16). The central line across the boxplots identifies the median, marking the dataset’s midpoint. The box itself demarcates the interquartile range, extending from the first quartile to the third quartile, encapsulating the central 50% of the data. The whiskers project from the box to the furthest data points not categorized as outliers and show the spread of the main body of the dataset. Raw data is provided as a Source Data file.
