Fig. 4: MYADM is not essential for viral RNA replication. | Nature Communications

Fig. 4: MYADM is not essential for viral RNA replication.

From: MYADM binds human parechovirus 1 and is essential for viral entry

Fig. 4

a Top: Schematic illustrating the comparison between virus infection and replicon assay, where replicon RNA was delivered by electroporation. Bottom: Schematic of the PeV-A1-nLuc-Replicon construct. b Time course of PeV-A1-nLuc virus infection and PeV-A1-nLuc-Replicon assay in MEF (WT: wild type; WT + MYADM-HA: MEF expressing human MYADM-HA) and 293FT (WT: wild type, ∆MYADM: MYADM knockout, ∆MYADM + MYADM-HA: human MYADM-HA-complemented MYADM knockout) cell lines. Data are presented as mean values +/− SEM, n = 3 or 4 biologically independent samples. Source data are provided as a Source Data file.

Back to article page