Table 1 Baseline characteristics of the UK Biobank analysis cohort, overall, by sex, and in those who developed any malignant cancer

From: Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank

Characteristics

All (N = 44,645)

Women (n = 23,274)

Men (n = 21,371)

Developed a malignant cancer (n = 4921)

Sociodemographic

Age (years)

57.0 (8.3)

57.0 (8.1)

57.1 (8.4)

60.6 (7.0)

Townsend deprivation, n (%)

    

Most deprived

9416 (21.1%)

4797 (20.6%)

4619 (21.6%)

1066 (21.7%)

Lifestyle

Physical activity level, n (%)

High ≥50 METs

7927 (17.8%)

3644 (15.7%)

4283 (20.0%)

852 (17.3%)

Smoking, n (%)

Never

24,481 (54.8%)

13,980 (60.1%)

10,501 (49.1%)

2220 (45.1%)

Current ≥15 cigarettes/day

1818 (4.1%)

752 (3.2%)

1066 (5.0%)

315 (6.4%)

Alcohol intake, n (%)

non-drinkers

3586 (8.0%)

2240 (9.6%)

1346 (6.3%)

359 (7.3%)

≥20 g/day

12,563 (28.1%)

3230 (13.9%)

9333 (43.7%)

1578 (32.1%)

Anthropometric

Standing height in cm

168.7 (9.3)

162.4 (6.4)

175.6 (6.9)

169.6 (9.1)

Body mass index (kg/m2)

27.3 (4.6)

27.0 (5.1)

27.6 (4.0)

27.6 (4.6)

Women’s Health

Parity in women, n (%)

Nulliparous

4257 (9.5)

416 (19.1%)

Age at first menarche in women, n (%)

<12 years

4467 (19.2%)

441 (20.3%)

Menopausal status in women, n (%)

Postmenopausal

16,580 (71.2%)

1760 (80.9%)

Hormone replacement therapy use in women, n (%)

Never

15,036 (64.6%)

1256 (57.7%)

Oral contraceptive pill use in women, n (%)

Never

4683 (20.1)

490 (22.5)

  1. Values are presented as mean (standard deviation) unless otherwise specified.