Fig. 1: Association of prior COVID-19 vaccination and risk of PCC categories 6 months following SARS-CoV-2 infection. | Nature Communications

Fig. 1: Association of prior COVID-19 vaccination and risk of PCC categories 6 months following SARS-CoV-2 infection.

From: Post-COVID conditions following COVID-19 vaccination: a retrospective matched cohort study of patients with SARS-CoV-2 infection

Fig. 1

Association of prior vaccination status with Post-COVID Conditions (PCC) was estimated among 161,531 vaccinated patients matched with 161,531 unvaccinated patients on Vaccine Safety Datalink site, date of SARS-CoV-2 positive test ( ± 7 days), age (exact year), sex, and severity of infection (hospital admission with COVID-19 diagnosis within 7 days of SARS-CoV-2 positive test). Relative risks (RR) and 95% confidence intervals (CI) were estimated by Poisson regression adjusted for matched variables and prior SARS-CoV-2 infection, race and ethnicity, Charlson comorbidity score, Medicaid status, influenza vaccination, and healthcare utilization in the year prior. Box sizes are inverse-variance weighted. PCC category ‘symptoms’ included headache, body ache/myalgia, fever/malaise/fatigue, lymphadenopathy, weight loss, or vertigo. To limit the impact of multiple testing, Bonferroni correction was applied to main analysis of 13 PCC categories, with 2-sided p-values at a level of significance of 0.004. *Significant with Bonferroni correction.

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