Fig. 4: Cellular oxygen dynamics in the WT and ∆kaiA strains.

Rhythms in growth and DO levels coincide with external LD cycles (green arrow) in the WT (a) and ∆kaiA (b). Rhythms are sustained in the WT after cells are transitioned to CL (green arrow) but not in the mutant (orange arrow). When grown under CL the WT (c) exhibits distinct endogenous rhythms in growth which coincide with oxygen cycling (green arrow). The rhythms are lost in ∆kaiA (d) where only a few random drops in oxygen levels are seen (orange arrow). Representative data from multiple runs are presented. 3 independent datasets for growth under CL (showing variability) for the WT and mutant have been provided as raw data (Source Data).