Fig. 1: Deep mutational scanning of SARS-CoV-2 bFP and FPPR. | Nature Communications

Fig. 1: Deep mutational scanning of SARS-CoV-2 bFP and FPPR.

From: Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning

Fig. 1

The fitness values of individual mutations at residues 808–855 of SARS-CoV-2 S were measured by deep mutational scanning in A Calu-3 cells and B Vero cells and are shown as heatmaps. Wild-type (WT) amino acids are indicated by black circles. “_” indicates nonsense mutations. Mutations in gray were excluded from our data analysis due to low frequency in the plasmid mutant library. Red indicates superior fitness, white is similar to WT, and blue has reduced fitness.

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