Fig. 8: Structural features of the L1 stalk and interactions with tRNA. | Nature Communications

Fig. 8: Structural features of the L1 stalk and interactions with tRNA.

From: Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk

Fig. 8

a The L1 stalk components uL9m (green), uL1m (purple) rRNA helix H76-77 (residues 2757-2790, light blue), as well as mL64 (magenta) interact with E/E-tRNA. The structure and interactions are different from T. thermophilus (PDB ID: 4V51) [https://doi.org/10.2210/pdb4V51/pdb]51 b Components of the L1 stalk modeled into their respective densities (shown as mesh). c Comparison of uL9m conformation with that of T. thermophilus uL9 (white PDB ID 4V51). d Model of uL1m stalk with uL9m in green and uL1m in purple, highlighting mitochondria-specific protein elements. e 2D diagram of uL9m showing interactions with E/E-tRNA (brown bars), rRNA (light-blue bars), uL1m (dark-blue bars). Conserved regions are shown in light and mitochondria-specific in dark colors. f 2D diagram of uL1m color-coded as in panel d.

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