Fig. 1: Structural derivatives of the endogenous 5-HT_2AR agonist serotonin (5-HT).

Ligand binding affinities (pKi) are indicated for Nitro-I, Met-I, OTV1 and OTV2 obtained in [³H]ketanserin competition binding experiments in CHO cells (n = 3). The data represent the mean ± SD (see methods section).