Fig. 1: Context, state-of-the-art and this work. | Nature Communications

Fig. 1: Context, state-of-the-art and this work.

From: Rapid and scalable photocatalytic C(sp2)–C(sp3) Suzuki−Miyaura cross-coupling of aryl bromides with alkyl boranes

Fig. 1

A The B-alkyl Suzuki−Miyaura cross-coupling is a powerful approach for the formation of C(sp3)‒C(sp2) bonds: the archetypal Pd-based catalysis typically requires refluxing solvents and relatively long reaction times. B Light-mediated B-alkyl Suzuki−Miyaura cross-coupling reaction via single-electron transmetalation: this approach is mainly restricted to the generation of stabilized radicals. C This work: photocatalyzed B-alkyl Suzuki−Miyaura cross-coupling with alkyl borane to append primary fragments onto arenes in short reaction times. dppf: 1,1 ′-Bis (diphenylphosphino)ferrocene. Pin: pinacol. Alk: alkyl group. Ar: aryl group. PC: photocatalyst.

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