Fig. 6: Expression of ITGAX and DNASE1L3 in the colonic lamina propria.
From: Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue
a Imaging Mass Cytometry (IMC) image of colonic folicle and adjacent lamina propria region showing the expression of DNASE1L3 (green), E-cadherin (orange) and nuclear counterstaining Iridium (dark blue). b High power images of the follicle shown in (a), further illustrating the expression of CD163 (magenta), CD68 (red) and ITGAX (blue) in regions from the Subepithelial dome (SED) (green box) and lamina propria (grey box). c, d IMC image of colonic lamina propria showing the distribution of E-cadherin (orange), CD68 (red), ITGAX (blue) alongside those of CD163 (magenta) and DNASE1L3 (green). Scalebars =100 μm. Findings shown in figure (a, b) are representative of 16 ROI. Findings shown in c and d are representative of 4 ROI.
