Fig. 7: CRs detected in clinical samples from Greater Houston.
From: Crykey: Rapid identification of SARS-CoV-2 cryptic mutations in wastewater
The mutation combinations for each wastewater CR are shown at the top of each panel. Cyan bars indicate the prevalence (left y-axis). The dotted blue lines (right y-axis) indicate the mean AF (right y-axis) of the CR in the clinical samples. The number of biologically independent clinical samples that the CR is prevalent are n = 5; 9; 163; 1115; 3830; 14; 20; 929; 1079; 7; 581; 845 for CR1 to CR12. The exact n for each CR per week is reported in the Source Data file. The error bars are defined as the range of the observed AF (right y-axis), with the top of the error bars showing maximum observed AF, and the bottom of the error bars showing minimum observed AF. The areas shaded in gray indicate the periods during which the CR was detected in the wastewater. The stacked bars to the right of the panels show the distribution of the PANGO lineages of the consensus genomes of clinical samples with CRs with each category shown in different colors. All Delta genomes are combined. All Omicron genomes other than BA.1.1, BA.1.15, BA.1.17, BA.1.18, and BA.1.20 are combined and denoted as Omicron. Source data are available for this figure and are provided in the Source Data file.
