Fig. 1: Copper (I) nitrene platform (CuNiP) for selective modification of methionine. | Nature Communications

Fig. 1: Copper (I) nitrene platform (CuNiP) for selective modification of methionine.

From: Copper(I)-nitrene platform for chemoproteomic profiling of methionine

Fig. 1

a Plausible reaction pathways for selective modification of methionine including metal-free ionic pathway and metal-catalyzed nitrene pathway with exquisite chemoselectivity for methionine via nitrene-pathway. b This work: Copper(I) nitrene platform (CuNiP) for selective modification of methionine for the formation of highly stable sulfonyl sulfimide product and its application in chemoproteomic profiling of human proteome. Figure 1, created with BioRender.com, released under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International license” (Agreement number: RQ26NYDQF6).

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