Fig. 2: Preparation and characterization of aAGd-NWs.
From: Chiral coordination polymer nanowires boost radiation-induced in situ tumor vaccination
a Schematic depiction of the process for preparing aAGd-NWs. Created with BioRender.com. b The Tyndall effect and photographs of the obtained aAGd-NWs. c HRTEM imaging of aAGd-NWs, scale bar = 50 nm. This experiment was repeated twice independently with similar results. d EDS mapping of the aAGd-NWs, scale bar = 20 nm. This experiment was repeated twice independently with similar results. e–g High-resolution Gd 4d (e), O 1 s (f), N 1 s (g) XPS spectra of aAGd-NWs, arbitrary units (a. u.). h FT-IR spectrum of GdCl3, free ara-AMP and aAGd-NWs, arbitrary units (a. u.). (i) Assessment of hydroxyl radicals produced by Vehicle, GdCl3, GGd-NCPs, and aAGd-NWs ([Gd] = 20 μM) under X-ray irradiation, as determined by the decay of MB (n = 3 experimental replicates). j Release profile of ara-AMP from aAGd-NWs in HEPES buffer containing 10% serum at different pH values (7.4, 6.0, 5.0) in vitro (n = 3 experimental replicates). All data were shown as mean ± SD. One-way ANOVA analysis of variance was used for multiple groups, and p values < 0.05 indicate statistically significant. Source data are provided as a Source Data file.
