Fig. 7: Structural comparison with relevant aptamers.
From: Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST
a Cartoon representation of the three-dimensional structure of the DIR2s aptamer in complex with OTB–SO3, and top and bottom views of the binding pockets with the ligand OTB–SO3. b Cartoon representation of the three-dimensional structure of the Malachite green aptamer in complex with TMR, and top and bottom views of the binding pockets with the ligand TMR. c Cartoon representation of the three-dimensional structure of the TMR3 in complex with 5-TAMRA, and top and bottom views of the binding pockets with the ligand 5-TAMRA. In a–c the ligands were shown as spheres. d Comparison of the binding interface areas of RhoBAST, TMR3, MG, and DIR2s aptamers in complex with their cognate ligands and ligand moiety. The binding interface area value for each pair is indicated above the bar. Source data for panel (d) is provided as a Source data file.
