Fig. 2: Partial correlation statistics measures of Isodendritic core integrity and demographic variables and CSF biomarkers.

Correlation statistics are corrected for age, sex, and education. Sex was dummy-coded as male (1) and female (0), so a positive correlation indicates greater values in males, and a negative correlation indicates greater values in females. MT magnetization transfer saturation, PD proton density, LC locus coeruleus, DR dorsal raphe, VTA ventral tegmental area, NbM nucleus basalis of Meynert. *p < 0.05, **p < 0.001, ***p < 0.0001 (These p-values are uncorrected for multiple comparisons and are presented only for transparency. They are not the primary metrics interpreted in the analysis but are here only to guide future studies). All statistical tests shown were two-tailed. Source data are provided as a Source Data file.