Fig. 5: Scatterplots between CSF pTau181 concentration and PLS brain scores for (a) NDI in pattern 1 and (b) ODI in pattern 2.

NDI neurite density index (orange), ODI Orientation dispersion index (purple). Higher brain scores indicate stronger expression of the covariance pattern. Standardized slope coefficients (β) and p-values are shown on each respective plot. Regression lines are shown with standard error shown in gray. All statistical tests shown were two-tailed. Source data are provided as a Source Data file.