Fig. 5: Surface plasmon resonance assay of HmAb64 binding to HIV-1 Env antigens. | Nature Communications

Fig. 5: Surface plasmon resonance assay of HmAb64 binding to HIV-1 Env antigens.

From: Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains

Fig. 5

a Titration of sCD4 (D1D2 domain) binding to various HIV-1 Env antigens (Bal gp120, A244 gp120, and BG505-SOSIP). b Binding kinetics of HmAb64 to HIV-1 Env antigens. c Binding kinetics of HmAb64 to HIV-1 Env antigens in the presence of increasing amount of sCD4(D1D2). d Binding kinetics of VRC01 to HIV-1 Env antigens in the presence of increasing amount of sCD4(D1D2).

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