Fig. 5: Loss of Rpgr hyperstabilises actin in the basal photoreceptor disc.
From: Ciliary tip actin dynamics regulate photoreceptor outer segment integrity
a, b A projection from a tomogram (left panel) and a slice through a tomographic reconstruction (right panel) of the basal disc of a wild type (a) and RpgrEx3d8 (b) photoreceptor to highlight the ciliary and disc membranes (cyan), microtubule-based axoneme (tan) and actin filaments (purple). c Actin filament length quantification in the basal disc of photoreceptor tomograms (N = 4 animals per group; ****p ≤ 0.0001; two-tailed, unpaired t-test; error bars denote SEM). (Scale bars; a, b = 100 nm). Source data are provided as a Source Data file.
