Fig. 1: Gray matter DMI parameters indicate microstructural changes between groups. | Nature Communications

Fig. 1: Gray matter DMI parameters indicate microstructural changes between groups.

From: Cerebral microstructural alterations in Post-COVID-condition are related to cognitive impairment, olfactory dysfunction and fatigue

Fig. 1

Box plots show the distribution of microstructural compartments within the entire gray matter. In patients with Post-COVID-Condition (PCC), a significant decrease in the extraneurite volume fraction (V-extra) was accompanied by a significant increase in the free-fluid fraction (V-CSF) when compared to Unimpaired Post-COVID (UPC) patients and the Healthy Non-COVID (HNC) group. Regarding the intraneurite volume fraction (V-intra), no statistically significant differences were present between groups. Group comparisons were performed using two-tailed ANCOVAs, with age and sex as nuisance covariates. The statistic was based on 46 HNC, 38 UPC, and 89 PCC cases. The center lines represent the median, box bounds show interquartile range (IQR), whisker borders indicate 1.5 x IQR. Dots represent individual subject values.

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