Fig. 2: RISER is more efficient than sequence-based adaptive sampling. | Nature Communications

Fig. 2: RISER is more efficient than sequence-based adaptive sampling.

From: Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER

Fig. 2

a, b Time in seconds (y-axis, log10-scale) taken to classify fixed-length DRS signals (n = 1000 DRS reads randomly sampled from the mRNA test set) by sequence-based adaptive sampling (AS) using basecalling and mapping to the protein-coding transcriptome (fuchsia) and by classification with RISER’s mRNA model (blue) using a GPU (a) or CPU (b). In the box plots, the lower and upper boundaries of the box are the first and third quartiles, with the median annotated with a line inside the box. The whiskers extend to the maximum and minimum values within 1.5 times the interquartile range. c Percentage of mRNA DRS signals classified as mRNA (y-axis) within a given time (x-axis) by AS (fuchsia) and RISER (blue). Source data are provided as a Source Data file.

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