Table 2 Generalized linear model for the effect of stimulation therapy, medications, and motor symptoms on beta band (13–30 Hz) circadian rhythms

From: Chronic intracranial recordings in the globus pallidus reveal circadian rhythms in Parkinson’s disease

 

Coefficient

Std. Err.

z

p > |z | 

Intercept term

1.2846

0.384

3.342

0.001

Stimulation location (dorsal: 1, ventral: 0)

−0.3737

0.194

−1.924

0.054

TEED (µJ)

254.7574

420.308

0.606

0.544

LEDD (mg)

−0.0001

0

−0.882

0.378

Nighttime Levodopa ER (use: 1, not used: 0)

0.3946

0.191

2.062

0.039

Sleep medication (used: 1, not used: 0)

−0.2965

0.201

−1.475

0.14

PD subtype (tremor/akinetic ratio)

0.0769

0.121

0.637

0.524

UPDRS

−0.0099

0.007

−1.519

0.129

  1. ER Extended-release, TEED total electrical energy delivered, LEDD levodopa equivalent daily dosage, UPDRS Unified Parkinson’s Disease Rating Scale, µJ microjoule, mg milligram. Source data is provided in the Source Data file.