Fig. 1: Summary of the snRNAseq approach utilized in this study. | Nature Communications

Fig. 1: Summary of the snRNAseq approach utilized in this study.

From: Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction

Fig. 1

a Post-mortem temporal cortex tissue from 24 individuals that comprise sex and age matched AD and control individuals were used in this study. b Development and optimization of nuclei isolation protocol for snRNAseq platform. c Well-established cell type markers were used to annotate nuclei clusters and d major brain cell types were visualized in UMAP plots. Figure 1/panels a and b Created with BioRender.com released under a Creative Commons Attribution-NonCommercial-NoDerivs license.

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