Fig. 1: Design of enantioselective anodic oxidative dienylation and allylation.
From: Enantioselective nickel-catalyzed anodic oxidative dienylation and allylation reactions
a Lewis acid-catalyzed anionic pathway and asymmetric electrolysis. b Advantages of asymmetric electrolysis. c Enantioselective nickel-catalyzed oxidative cross-coupling reactions. d Optimization of the reaction conditions. Reactions were carried out with 1a (0.1 mmol), 2a (0.3 mmol), nBu4NPF6 (0.15 mmol), quinuclidine (0.05 mmol), Ni(OAc)2·4H2O (10 mol%), L (10 mol%), Cp2Fe (10 mol%), and DCM/TFE = 2:1 (3 mL) at 25 °C in an undivided cell, 3 h, E/Z > 20:1. TFE, 2,2,2-trifluoroethanol.
