Table 1 Enantioselective anodic oxidative dienylation with allenylsilanes

From: Enantioselective nickel-catalyzed anodic oxidative dienylation and allylation reactions

  1. Unless otherwise specified, all reactions were carried out using racemic benzoxazolyl acetate 1 (0.1 mmol), allenylmethylsilane 2 (0.30 mmol), nBu4NPF6 (0.15 mmol), quinuclidine (0.05 mmol), Ni(OAc)2·4H2O (10 mol%), L9 (10 mol%), Cp2Fe (10 mol%), and DCM/TFE = 2:1 (3 mL) at 25 °C for 3 h under constant-current conditions in an undivided cell. a0.5 mmol scale, 3.5 h. bHCO2H (20 mol%). cDCE/TFE (3 mL, 2:1) at 40 °C. dL4 (10 mol%). eAllenylmethylsilane 2 (0.60 mmol). f6 h. gNi(OAc)2·4H2O (20 mol%), L9 (20 mol%), 2 (0.6 mmol) at 50 oC.
Back to article page