Table 2 Effect of six months of consumption of multiple-micronutrient fortified rice on alpha (pairwise difference) and beta diversity (pairwise distance) metrics

From: Faecal microbiota of schoolchildren is associated with nutritional status and markers of inflammation: a double-blinded cluster-randomized controlled trial using multi-micronutrient fortified rice

Alpha diversity

   

Mann-Whitney U

FDR p-value

Shannon index

Intervention group

Placebo vs. UR-improved

6498

0.0672

Placebo vs. UR-original

7844

0.2221

UR-improved vs. UR-original

5472

0.0104

Pielou’s evenness

Intervention group

Placebo vs. UR-improved

6953

0.1349

Placebo vs. UR-original

8544

0.0326

UR-improved vs. UR-original

5135

0.0016

Faith PD

Intervention group

Placebo vs. UR-improved

7256

0.3346

Placebo vs. UR-original

5923

0.0347

UR-improved vs. UR-original

7834

0.1400

Beta diversity

   

Mann-Whitney U

FDR p-value

Bray Curtis

Intervention group

Placebo vs. UR-improved

5871

0.0007

Placebo vs. UR-original

9560

0.0000

UR-improved vs. UR-original

10471

0.0000

Weighted UniFrac

Intervention group

Placebo vs. UR-improved

7291

0.3661

Placebo vs. UR-original

10864

0.0000

UR-improved vs. UR-original

10908

0.0000

Unweighted UniFrac

Intervention group

Placebo vs. UR-improved

5928

0.0015

Placebo vs. UR-original

8453

0.0334

UR-improved vs. UR-original

9636

0.0000

Jaccard

Intervention group

Placebo vs. UR-improved

5768

0.0005

Placebo vs. UR-original

8770

0.0067

UR-improved vs. UR-original

10055

0.0000

  1. The q2-longitudinal plugin was used to compare baseline and endline data in terms of alpha and beta diversity group significance using the pairwise difference and pairwise distance tests, respectively. A two-sides Mann-Whitney U test was used. P values were adjusted with Benjamini-Hochberg procedure. Adjusted P values less than 0.05 are considered statistically significant. It evaluated the different changes in faecal bacterial diversity in children in the three intervention groups (Placebo n = 128, UR-improved n = 122, UR-original n = 114) between baseline and endline.
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