Fig. 9: Transcriptomic analysis of 4T1 tumor tissues before and after HBO-coupled PTT treatment. | Nature Communications

Fig. 9: Transcriptomic analysis of 4T1 tumor tissues before and after HBO-coupled PTT treatment.

From: Hyperbaric oxygen enhances tumor penetration and accumulation of engineered bacteria for synergistic photothermal immunotherapy

Fig. 9

a Volcano plot of all the DEGs between the control group and the treated (“EcN-cypate + HBO + laser”) group. b Histogram presenting the GO enrichment analysis results of some selected DEGs between the control group and the treated group. c Heat map of the selected DEGs between the control group and the treated group. Red and blue colors indicate the up-regulation and down-regulation, respectively. d Dot plot illustrating the KEGG enrichment analysis results of some selected DEGs between the control group and the treated group. Statistical significance in a, c, and d was calculated via two-tailed Student’s t test. n = 3 mice.

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