Table 1 Characteristics of all submitted CRKP with different carbapenemase genes. Full data available in Supplementary Data 1
From: International and regional spread of carbapenem-resistant Klebsiella pneumoniae in Europe
Clonal lineages | Total number of isolates (% of total) | Countries with more than 10 isolates | Number of different countries | STs with more than 10 isolates | Carbapenemase gene variants and number of isolates | No carbapenemase found | |||
|---|---|---|---|---|---|---|---|---|---|
Class A | Class B | Class D | Two carbapenemases | ||||||
ST258/512 | 204 (30%) | Italy (n = 74) Greece (n=58) Spain (n=58) | 6 | ST512 (n = 116) ST258 (n = 73) ST1519 (n = 12) | blaKPC-2 (n = 69) blaKPC-3 (n = 134) blaKPC-36 (n = 1) | blaNDM-1 (n = 1) | 1 | ||
ST11/437/340 | 116 (17%) | Greece (n = 41) Serbia (n = 37) Spain (n = 36) | 5 | ST11 (n = 78) ST437(n = 33) | blaKPC-2 (n = 4) | blaNDM-1 (n = 47) blaVIM-1 (n = 1) | blaOXA-48-like (n = 60) | 3 | 7 |
ST101 | 87 (15%) | Serbia (n = 56) Romania (n = 17) | 5 | ST101 (n = 83) | blaKPC-2 (n = 2) blaKPC-3 (n = 5) | blaNDM-1 (n = 4) | blaOXA-48 (n = 66) | 2 | 12 |
ST307 | 71(10%) | Spain (n = 33) Italy (n = 24) | 5 | ST307 (n = 68) | blaKPC-2 (n = 16) blaKPC-3 (n = 27) | blaNDM-1 (n = 4) blaVIM-1 (n = 1) | blaOXA-48 (n = 22) | 1 | |
ST15 | 42 (6%) | Spain (n = 34) | 5 | ST15 (n = 38) | blaKPC-2 (n = 1) blaKPC-3 (n = 1) | blaNDM-1 (n = 2) blaVIM-1 (n = 1) | blaOXA-48-like (n = 37) | 1 | 1 |
ST147 | 40 (6%) | Spain (n = 20) Greece (n = 15) | 6 | ST147 (n = 35) | blaKPC-2 (n = 12) blaKPC-3 (n = 1) | blaNDM-1 (n = 13) blaVIM-1 (n = 6) | blaOXA-48-like (n = 21) | 14 | 1 |
ST14 | 24 (4%) | Türkiye (n = 24) | 1 | ST14 (n = 20) | blaNDM-1 (n = 12) | blaOXA-48-like (n = 24) | 12 | ||
ST405 | 5 | 2 | blaKPC-2 (n = 2) | blaOXA-48 (n = 3) | |||||
ST37 | 4 | 3 | blaOXA-48 (n = 4) | ||||||
ST45 | 4 | 2 | blaKPC-3 (n = 2) | blaOXA-48 (n = 2) | |||||
ST17 | 2 | 2 | blaOXA-48 (n = 2) | ||||||
Other | 84 (12%) | Greece (n = 47) Serbia (n = 10) Türkiye (n = 10) | 7 | ST39 (n = 30) ST395(n = 14) | blaKPC-2 (n = 33) blaKPC-3 (n = 4) | blaNDM-1 (n = 13) blaVIM-1 (n = 14) | blaOXA-48-like (n = 25) | 5 | |
