Fig. 2: No evidence for evolution in cohort 1 animals initiating ART at 27 dpi.
From: No evidence for ongoing replication on ART in SIV-infected macaques
The scatter plot at each time point shows the distribution of p-distances from the SIVmac239 founder with black lines corresponding to the linear regression slopes (mutations per site per day) and the grey bands to the 95% confidence intervals around the slope (A). The evolutionary rates during ART are not significantly different from zero in any animal (two-sided t-test). The phylogenetic trees show intermixing of nFL SIV DNA sequences obtained from PBMCs at 45 dpi (blue) and 285–345 dpi (red) in each animal (B). Asterisks indicate sequences with short indels. Source data are provided as a Source Data file.
