Fig. 3: Phylogenetic tree and highlighter alignment show lack of evolution in cohort 2 animals starting ART at 10 dpi. | Nature Communications

Fig. 3: Phylogenetic tree and highlighter alignment show lack of evolution in cohort 2 animals starting ART at 10 dpi.

From: No evidence for ongoing replication on ART in SIV-infected macaques

Fig. 3

The neighbor-joining tree combining all nFL SIV DNA sequences obtained from PBMCs for all ten RMs has a star-like structure with few shared mutations between sequences. Single nucleotide polymorphisms (SNP) from the SIVmac239 founder sequence [red for adenine (A), blue for cytosine (C), orange for guanine (G), and green for thymine (T), including potential APOBEC-mediated mutations (purple)] are indicated in the highlighter plot. Asterisks indicate sequences with short indels.

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