Fig. 2: Assessment using synthetic data. | Nature Communications

Fig. 2: Assessment using synthetic data.

From: Solution-state methyl NMR spectroscopy of large non-deuterated proteins enabled by deep neural networks

Fig. 2

a, b Exemplar synthetic data without processing by the FID-Net DNNs (left column) and with FID-Net based processing (right column). a A synthetic spectrum where we have a similar number of signals to HDAC8 (42 kDa). b A spectrum that has a similar number of signals to MSG (81 kDa). One hundred distinct spectra with a similar number of signals to those shown in a or b are generated. These are then analysed using the FID-Net approach and the resulting spectra are peak picked. From FID-Net analysed spectra peaks are picked and compared to ground truth values. From picked peaks, true positive, false positive and false negative rates of peaks are calculated (only considering isolated peaks) and plotted (c, d). Full details are given in the Methods section.

Back to article page