Fig. 8: DGC identifies early-stage AD patient brain sections.
From: A probe for NIR-II imaging and multimodal analysis of early Alzheimer’s disease by targeting CTGF
a The fluorescence imaging of cortex regions in brain sections from an early stage of AD patient (AD) and Healthy control (HC) after staining with DGC (red fluorescence) and FITC-labeled CTGF antibody (green fluorescence). The merge pictures show the colocalization of DGC and CTGF. Scale bar = 50 μm. b The fluorescence (FL) intensity of DGC in (a) analyzed by ImageJ software. Data were presented as mean ± SD from three independent sections of the same case (n = 3). Student’s t-test. c ICP-MS analysis of DGC (Au) content of per cm2 after incubating DGC with indicated brain sections. Data were presented as mean ± SD from three independent sections of the same case (n = 3). Student’s t-test. Source data are provided as a Source Data file.
