Fig. 2: Substrate scope of electrophilic reagents. | Nature Communications

Fig. 2: Substrate scope of electrophilic reagents.

From: Palladium-catalyzed Suzuki-Miyaura cross-couplings of stable glycal boronates for robust synthesis of C-1 glycals

Fig. 2

General reaction conditions: 12b (0.12 mmol), 14 (0.10 mmol), Pd(PPh3)2Cl2 (5.0 mol%), K3PO4 (3.0 equiv), DMF (2.0 mL), 33 °C, 48 h, N2, isolated yields. aMethyl 4-iodobenzoate was used. bMethyl 4-(trifluoromethylsulfonyloxy)benzoate was used. cNMR yields. TIPS: Triisopropylsilyl groups. [X]: Halogens or pseudohalogens. C: Carbon electrophiles. Bpai: Pinanediol–boronic acid esters.

Back to article page