Fig. 3: Substrate scope of oligopeptide electrophilic reagents. | Nature Communications

Fig. 3: Substrate scope of oligopeptide electrophilic reagents.

From: Palladium-catalyzed Suzuki-Miyaura cross-couplings of stable glycal boronates for robust synthesis of C-1 glycals

Fig. 3

General reaction conditions: 12b (0.12 mmol), 16 (0.10 mmol), Pd(PPh3)2Cl2 (5.0 mol%), K3PO4 (3.0 equiv), DMF (2.0 mL), 33 °C, 48 h, N2, isolated yields. a50.0 mol% Pd(PPh3)2Cl2 was used. reaction conditions, showcasing the favorable balance of reactivity and stability exhibite by the glycal boronates and their potential for broader impacts. TIPS: Triisopropylsilyl groups. AA: Amino acids. Bpai: Pinanediol–boronic acid esters.

Back to article page