Fig. 5: Ccka and Cckb redundantly function as FSH-RH. | Nature Communications

Fig. 5: Ccka and Cckb redundantly function as FSH-RH.

From: Identification of the FSH-RH as the other gonadotropin-releasing hormone

Fig. 5

a Gross morphology of the ovaries and testes of ccka and cckb single and double KO. b, c The ovarian size (b) and testis size (c) of each genotype normalized by body weight (n = 6 fish; ***p = 1.4e-6; **p = 0.0023). df qRT-PCR of the medaka pituitary of each genotype (d, fshb; e, lhb; f, tshb; n = 6 fish; ***p = 4.4e-4; **p = 0.0015). The data are mean ± SEM. ***p < 0.001, **p < 0.01, N.S. not significant, two-sided Dunnett’s test (bf). Source data are provided as a Source Data file.

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