Fig. 2: Patterns of immune regulation across pediatric brain tumors. | Nature Communications

Fig. 2: Patterns of immune regulation across pediatric brain tumors.

From: Immuno-oncologic profiling of pediatric brain tumors reveals major clinical significance of the tumor immune microenvironment

Fig. 2

a Heatmap of pan-cancer gene signatures of anti-tumor and pro-tumor immune processes from Bagaev et al. across 811 pediatric brain tumors from the PBTA. (HGG: high-grade glioma; LGG: low-grade glioma). b Pearson correlation matrix of pan-cancer immune gene expression signatures from Bagaev et al. c, d Pearson correlation matrix of TIS with (c) PROGENy cellular pathway activation scores and (d) COSMIC Single Base Substitution (SBS) mutational signatures.

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