Fig. 2: Reduced liver inflammation in HFD-fed Lyz-IFNγR2−/− mice. | Nature Communications

Fig. 2: Reduced liver inflammation in HFD-fed Lyz-IFNγR2−/− mice.

From: IFNγ-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease

Fig. 2

Multiplexed-Luminex analysis of liver cytokines was performed in male Lyz-IFNγR2−/− and WT mice at 6 ~ 7 months of age following 10 weeks of an HFD. A IL-1β, IL-7, IL-15, IL-17, IFNγ, and vascular endothelial growth factor (VEGF) levels in the liver (n = 3 ~ 4 HFD-WT and 6 ~ 8 HFD-Lyz-IFNγR2−/− mice). B IL-9, KC (murine IL-8 homolog), and monokine-induced by IFNγ (MIG) levels in the liver (n = 4 HFD-WT and 7 ~ 8 HFD-Lyz-IFNγR2−/− mice). C IL-12 (p40) and IL-12 (p70) levels in the liver (n = 4 HFD-WT and 8 HFD-Lyz-IFNγR2−/− mice). Data are presented as mean ± SEM values. The statistical significance of the difference in mean values was determined using a two-tailed Student’s t-test.

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