Fig. 2: mRNA deadenylation is impaired in mouse and human oocytes matured in vitro.
From: Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes
Histogram of poly(A) tails length of all transcripts (a, e), transcripts of the in vitro MII oocyte-upregulated genes (b red genes (n = 4789) in Fig. 1c; f orange genes (n = 3072) in Fig. 1h), transcripts of the in vitro MII oocyte-downregulated genes (c blue genes (n = 343) in Fig. 1c; g blue genes (n = 1352) in Fig. 1h), or transcripts of Bmp15 in in vivo or in vitro MII oocytes in mice (a–d) or humans (e–h). Histograms (bin size = 1 nt) are normalized by counts of reads mapped to protein-coding genes in the mitochondria genome. Transcripts with poly(A) tails of at least 1 nt are included in the analysis. Transcripts with poly(A) tail lengths greater than 250 nt (150 nt for d and 200 nt for h) are included in the 250 nt (150 nt for d and 200 nt for h) bin. Source data are provided as a Source Data file.
