Fig. 2: Exome-wide association analysis of rare and common protein-coding genes with brain iron across 26 regions. | Nature Communications

Fig. 2: Exome-wide association analysis of rare and common protein-coding genes with brain iron across 26 regions.

From: Whole-exome sequencing identifies protein-coding variants associated with brain iron in 29,828 individuals

Fig. 2

a Significance levels of genes that are mapped from rare variants. b Significance levels of genes that are mapped from common variants. The p-values reported are two-sided and unadjusted. The x-axis represents the brain regions analyzed in the current study (L and R represent left and right brain regions), and the y-axis represents the \({-\log }_{10}\) p-values of each gene. The gray dashed line is the exome-wide significance threshold, based on the Bonferroni-corrected p < 0.05. Genes in red are discovered by the current study, and in black are previously reported. MAF minor allele frequency, R right, L left.

Back to article page